The academic structure of IIIT Kalyani exhibits the diversity, comprehensiveness, and depth befitting an institution of its age and stature. The programme/course offered at the institute have the flexibility to evolve and change in response to new requirements. They serve the dual purpose of building a solid foundation of knowledge and of enhancing confidence, creativity and innovation in its students.

A unique attribute of IIIT Kalyani's academic structure is the autonomy enjoyed by the faculty in designing and structuring their curriculum and courses .A favourable student-teacher ratio ensures productive, personal contact between the student and the teacher.

Finally, credit-based academic programmes offer flexibility to students to progress at their own pace. This system ensures an academic programme which is dynamic and constantly evolving and which reflects the institute’s commitment to stay in tune with the expanding frontiers of knowledge worldwide. The institute provides high quality of education, and it ensures that its students are also of exceptionally high calibre. Admission to IIIT Kalyani is enabled through Joint Entrance Examination (JEE) only for the undergraduate programme.

IIIT Kalyani's B.Tech. programme admits 130 students for only one of its discipline, Computer Science and Engineering (CSE). Seats are filled up through Joint Seat Allocation Authority (JoSAA) after qualifying JEE (Main) examination administered by Central Board of Secondary Education (CBSE).